Yeah, in fact, many people swear by bare wire. The connector can't improve upon the signal's performance, but it adds a tremendous amount of convenience if you switch out HT components frequently.
Some people say that it colorizes the sound out of the speakers but I'm guessing if you use that high quality WBT solder from parts express - that's not so much anyways, you'll have no issues of that w/ tinning. Also some people like using gold spray on their lines too - supposedly adds connectivity.
But w/ all these added costs, it just might be cheaper to purchase premade StarQuad wires.