Now why would you want to go and do that?
To my knowledge no there is not a setting that would allow that. You could open the case and flip the display upside down but I am not sure that case would like that. (little pieces that wouldnt fit.
KyleS
It depends on what operating system you run, chipset, etc. I know video driver utilities, such as those provided with ATI and Matrox cards allow for inversion. It may also be possible with a 3rd party app (assuming you're running some Windows variant).