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  1. Dave Upton

    Is it time to talk about coronavirus?

    As a resident of the notoriously libertarian state of Texas, I'm very nervous about our governor trying to reopen the economy here tomorrow. We've seen ample evidence that the only reason Texas isn't in a worse position today is the actions of our local judges preempting what the state and White...
  2. Dave Upton

    Is it time to talk about coronavirus?

    As is the risk with any science. It's more suspicion at this point on my side, but I have a hard time believing community spread wasn't happening between Christmas and March.
  3. Dave Upton

    Is it time to talk about coronavirus?

    The antibody tests will be very telling, as there are likely a ton of people already exposed in the past.
  4. Dave Upton

    Is it time to talk about coronavirus?

    HIV is highly polymophic, meaning it has a highly variable protein shape at the binding site. Imagine each virus has a "key" while your cells have a lock. The key of each HIV is slightly different. Vaccines don't work well here because they require the virus to be somewhat consistent in the...
  5. Dave Upton

    Is it time to talk about coronavirus?

    Saw this today and thought it very apropos.
  6. Dave Upton

    Is it time to talk about coronavirus?

    I had a coworker of mine get exposed via the spouse of his wife's ex, who they share custody with. He was pretty sure he had a mild case, starting last Wednesday with fevers and not much else. It quickly progressed to him having horrible aches, sore throat and spitting up blood. His breathing...
  7. Dave Upton

    Is it time to talk about coronavirus?

    That's why the antibodies like I posted above are so important, that is the most realistic near-term treatment that is curative while we wait on a vaccine.
  8. Dave Upton

    Is it time to talk about coronavirus?

    Some very exciting news out of California. I just hope this can get through safety testing and into compassionate use ASAP: Monoclonal antibodies are actually a proven and "old" methodology, they have just taken a long time to develop historically. The key breakthrough here was not...
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