I have had a really good Epson scanner that used to work great with Mac, but suddenly ceased working early last year. I have a feeling that when OS X was updated to 10.5, it did something to affect the scanner drivers. Even the Epson site doesn't have drivers for the my model to work with the new version of Leopard. In any case, it seems that Neatdesk has just released their Neatdesk for Mac. It looks pretty phenomenal, and I am awaiting reviews on Amazon before deciding to make the purchase. Here is information on the scanner: Click Here.