When the child wellfare agency comes to the Simpson household and find Maggie drinking out of the dog bowl while a note is taped to her chest that says "I'm a stupid baby."
Child Welfare Agent: "Stupid babies need the most help."
Forgive the inaccuracies:
From a Halloween episode:
Marge: "Without warning I was abducted by aliens!"
flashback to-
Alien Spaceship: "Warning! Warning! Prepare to be abducted!"
When the family moved to Cypress Creek (upstate somewhere):
Homer: "I tackled a loafer at work today."
When...
From my personal favorite episode: You Only Move Twice...
Hank Scorpio: "Like my shoes? Look in your closet, you've got a pair just like 'em. Don't like 'em, then neither do I!"
Scorpio takes off his shoes and hurls them.
Hank Scorpio: "Good-bye shoes! Did you ever see a man say good-bye to...