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All FireWire cards are internal :) Some motherboards have support built-in, just like USB. If you upgrade in the near future, it would be something to look for. There are all sorts of quality differences, but they don't necessarily have anything to do with whether they are external or...

In general, there is the simple practical matter of having to pop open the box and have a spare slot for the internal card. There is a slight chance of some hardware conflict for whatever particular combination of cards you have. USB and FireWire are designed to have a bunch of things plugged...