How about Futurama? Not sure if anyone has mentioned it yet. That's another show that was cancelled before it really should have been, but at least they still managed to get over 70 episodes made. Anyway, it is hilarious, and often quite intelligent (it's what I call "intelligently silly," at least). And another vote here for Red Dwarf, one of the funniest shows ever created. Actually, Futurama and Red Dwarf are similar in that both are uproariously funny and pretty decent science fiction shows at the same time. They'll start out with a genuinely interesting sf idea, and then spoof the heck out of it. I'd also recommend Firefly. Very unique show, and a much better experience on DVD than on TV, where the original pilot was actually the last episode shown. Funny story: My dad and I caught most of the Firefly episodes when they originally aired, and after he saw the pilot, he said, "If they'd shown that one first, it would have been a hit." He now owns the DVD set and has watched every single episode at least three times. And I agree; I think that was one of the major reasons it didn't do that well.