My little (18 lb) dog seems to be allergic to her annual shots. The vet always gives her all her shots at once, and within a day or less she's very lethargic and not eating or drinking, just wants to cuddle and not play or anything. After a couple of days of this I call the vet in a panic and take her in. He gives her some other shot and she seems to recover. I don't know what he gives her, presumably prednisone. While I'm convinced she's had a potentially life-threatening allergic reaction, the vet seems to think she's just sore from having had the shot. She's going on 10 years old and I have to admit that fear of this has prevented me from taking her in for her shots for the last 2 or 3 years. I know I should take her in again soon, but really fear that her advancing age may make her even more susceptible than before and I don't want to lose her. She's a strictly indoor dog, only goes out to go potty and has virtually no contact with other dogs. I do also have a mostly outdoor cat, however, which she is exposed to on a regular basis, and we have had the occasional gopher in the back yard. I'd really like some advice on this--should we space out the shots instead of giving them all at once? Is there one particular immunization that is prone to cause allergic reactions? Is it safe just to not take a chance and quit giving her shots alltogether? Any help or advice would be very much appreciated.