The problem with T-nuts is that the MDF isn't a very good material for the cleats on the back of the T-nut to grib, so they can spin on you when you try to tighten them or remove them, not good. I just used pre-drilled holes and mushroom head wood screws, because I don't plan on removing the driver much.
I tried T-nuts and lost interest real quick. I may try threaded inserts in the future. I've got tons of them. But I mostly just pre-drill and use black oxide panhead screws.