I'm not so sure about that. Yes, Johnny Depp is very popular internationally, but in an American western parody? I'm not expecting it to break records overseas either. It'll likely do better there than here, but with a $225 million price tag plus advertising here and over there, we're talking about at least $350 million overall costs meaning it would need a gross of $520 million to break even. I don't see that happening.
The latest Pirates movie made more than a billion dollars and about 3/4 of that came from the international market. This movie is more or less being marketed as Pirates Of The Caribbean: The Old West (and probably even more so internationally) so I think it can pretty easily pull in half of what a Pirates movie did even with the 'hindrance' of being a western.
And since this thread is for people who don't watch TV today to say that it's all bad, the movie business discussion should be moved to a more appropriate thread.