I saw in last weekend's paper that Notre Dame was a double-digit underdog in numerous games already, including USC, Michigan, Michigan State and Purdue. The paper suggested that Charlie Weiss may want to re-apply for his coordinator job with the Patriots very soon. It warms this Wolverine fan's heart to see that.
Michigan and OSU should once again be the main contenders for the Big Ten. Iowa lost a lot of players from last season. Most of Michigan's offense returns, with the exception of Braylon Edwards and David Bass. However, they are quite deep at receiver and always seem to have an abundance of offensive linemen, so they should be able to fill in those holes easily. They also have a young, deep and talented group of running backs. The defense lost several players, but considering the way it's played the past few years, that could be a good thing.
Also, their non-conference schedule is Wisconsinesque, although they did (barely) avoid scheduling any catholic girls schools.