I am currently using the Harmony 659 & feel it it one of the best investments for my theater. Not only does it get rid of multiple remotes, it makes the theater user friendly for the rest of the family. Before I had a "cheat sheet" for my family so they could use the theater. I also got many calls at work for instructions.
With the Harmony, they can just press a button for the activity they want. "Watch a Movie" and it turns on the receiver, DVD & projector, then puts them all on the correct settings. The remote is easily programed from their web site and the default buttons and actions are logical. You are also given the option to change or add any function, so you won't loose any of your current functions.
Originally I wondered if the cost of the remote was worth getting rid of the inconvenience of having 5 or 6 remotes laying around. It is definitely worth making the theater easy to use for everyone in the family

Dave