A Google search for SDKYR.DLL turned up a longish thread on a spyware discussion forum
here. Without going into all the details revealed by HiJack This, I'd certainly take a stab a running some good anti-spyware programs on the system. Spybot Search & Destroy and Ad Aware are two top programs with free versions. Spybot contains an immunize function that actively protects your system from threats, but which does not update its spyware database automatically. Ad Aware (free version) doesn't actively protect your system or update itself, but it is very good at finding and removing threats. Microsoft Anti-Spyware actively protects a system and automatically updates both the program and the anti-spyware database. But I believe it is only available for Windows XP (and possibly 2000.)
Regards,
Joe