Plenty...loss of bone mass...osteoperosis...degenerative joint diseases...dental problems...which is precisely what my (sadly misquoted) point was from the beginning. Beautiful as these pictures are, subtract not 10 but 20 pounds and that's what she will look like in person. After reading a bit I applaud Scarlett for at least attempting attempting to fight the Hollywood lolipop girl ideal. (Big round head...stick figure body). At least she acknowledges that the industry puts pressure on actresses to stay small. It's not just their business. They have very little choice if they want to work. It goes all the way back to Judy Garland and probably farther. And the "I look fat" cliche that we've all heard from at least one woman is greatly due to this problem. A local radio show mentioned a while back that they were at an event with Courtney Thorne Smith and they couldn't believe how scrawny she looked. Their point was that she looks relatively normal on screen, so just imagine how Calista Flockhart looks in person. I think that maybe Calista is naturally that way and the rest of the cast was left with having to compete because they (as well as the powers) felt that they looked overweight by comparison. The two dimensional nature of film, TV & print messes with our perception which is why this size issue has gotten out of control. Eye candy can be a wonderful thing but the reality is completely different. Even the CDC has a skewed notion of fitness. Punch your current weight into their calculator (your real weight if your were to step on a scale at this very moment) and see what it says.