I'm wondering who else out there has some mistake (or a good decision, for that matter) you have made that is so profound you now believe it significantly altered your entire life? Particularly something that couldn't have been painfully obvious at the time, like committing a serious crime. I've been coming to terms with some actions over 25 years ago which now appear to have been one of, if not the most significant in determining the path of my life, and possibly even someone else's. Deep stuff on an HTF evening. Any contributions?